The Prime Detective is the lead Detective in The Sanctuary. They would investigate the bigger cases and be the first called for any Sanctuary business.
List of Prime Detectives
- Skulduggery Pleasant: Unknown - May 2008. Fired for calling Thurid Guild a traitor
- Remus Crux: May 2008 - October 2008. Dropped after his mind broke from glancing at a Faceless One
- Davina Marr: Unknown - September 2009. Let go after commiting mass murder by blowing up the Irish Sanctuary using Myron Stray.
- Skulduggery Pleasant: December 2009 - present
- Davina Marr: Unknown - 2009. Transferred to the Irish Sanctuary